Eisenia fetida Protease-III-1 Functions in Both Fibrinolysis and Fibrogenesis
نویسندگان
چکیده
منابع مشابه
Eisenia fetida Protease-III-1 Functions in Both Fibrinolysis and Fibrogenesis
The fibrinolytic function of earthworm protease-III-1 (Ef P-III-1) has been studied in recent years. Here, we found that Ef P-III-1 acted not only in fibrinogenolysis, but also in fibrogenesis. We have used Ef P-III-1 to hydrolyze fibrinogen, and to activate plasminogen and prothrombin. Based on the N-terminal sequences of the hydrolytic fragments, Ef P-III-1 was showed to specifically recogniz...
متن کاملIn situ localization and substrate specificity of earthworm protease-II and protease-III-1 from Eisenia fetida.
Recently, the function in fibrinolysis of earthworm proteases has been studied. In our experiments, earthworm protease-II (EfP-II) and earthworm protease-III-1 (EfP-III-1) were isolated and purified from Eisenia fetida. As shown by the assay of sections of the earthworm on fibrin plates, the enzymic activity was mainly detected around the clitellum. In the presence of anti-EfP-II or anti-EfP-II...
متن کاملEcotoxicity of Sodium Arsenite on Eisenia Fetida
In this study, we performed ecotoxicity tests of sodium arsenite on soil invertebrate Eisenia fetida. Initially, broad range of sodium arsenite (0.1, 1, 10, 100mg/ml) was tested for mortality of E. fetida after 24 hours in filter paper test. The narrow range doses (0-1mg/ml) were further tested to determine the EC50 and LD50. The EC50 dose of sodium arsenite was considered at which 50% of earth...
متن کاملLiquid Chromatographic Characterization of TNT in Eisenia fetida Liquid Chromatographic Characterization of 2,4,6- Trinitrotoluene Bound Residues Extracted from Eisenia fetida
The nitroaromatic compound TNT is a common component in military munitions because of its chemical stability and comparatively safe method of manufacture. In living systems, TNT is rapidly metabolized into four identifi able and extractable compounds (2-amino-4,6dinitrotoluene, 4-amino-2,6-dinitrotoluene, 2,4-diamino-6-nitrotoluene, and 2,6-diamino-4-nitrotoluene). Exposing model organisms to T...
متن کاملToxicity and bioaccumulation of ethofumesate enantiomers in earthworm Eisenia fetida.
Earthworms represent an important food source for many vertebrates and as a result, predators may encounter toxic effects via the food chain from consumption of contaminated worms. Therefore, including an assessment of xenobiotic to worms in risk assessment procedures is advisable. Here we studied the acute toxicity, bioaccumulation and elimination of ethofumesate enantiomers in earthworm, Eise...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biomedicine and Biotechnology
سال: 2007
ISSN: 1110-7243,1110-7251
DOI: 10.1155/2007/97654